About Immunoglobulin lambda-like polypeptide 5
Immunoglobulin lambda-like polypeptide 5 (IGLL5) is a protein
from Homo sapiens identified by UniProt accession
B9A064, 214 residues long.
MolForge cross-references it against 0 known binders and
245 disease associations.
Target properties
| Protein name | Immunoglobulin lambda-like polypeptide 5 |
|---|
| UniProt accession | B9A064 |
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| Gene | IGLL5 |
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| Organism | Homo sapiens |
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| Length | 214 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (245)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.45
- lymphoid leukemia · score 0.41
- blood protein measurement · score 0.40
- leukemia · score 0.24
- neutrophil percentage of leukocytes · score 0.16
- lymphocyte percentage of leukocytes · score 0.15
- hematopoietic and lymphoid system neoplasm · score 0.15
- neoplasm · score 0.08
- multiple myeloma · score 0.08
- Systemic lupus erythematosus · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-B9A064-F1 | alphafold | PREDICTED | 75.39 | — |
Amino-acid sequence (214 residues)
MRPKTGQVGC ETPEELGPGP RQRWPLLLLG LAMVAHGLLR PMVAPQSGDP DPGASVGSSR SSLRSLWGRL LLQPSPQRAD PRCWPRGFWS EPQSLCYVFG TGTKVTVLGQ PKANPTVTLF PPSSEELQAN KATLVCLISD FYPGAVTVAW KADGSPVKAG VETTKPSKQS NNKYAASSYL SLTPEQWKSH RSYSCQVTHE GSTVEKTVAP TECS
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