TBC1 domain family member 3L (TBC1D3L)

About TBC1 domain family member 3L

TBC1 domain family member 3L (TBC1D3L) is a protein from Homo sapiens identified by UniProt accession B9A6J9, 549 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	TBC1 domain family member 3L
UniProt accession	B9A6J9
Gene	TBC1D3L
Organism	Homo sapiens
Length	549 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.07
serum urea measurement · score 0.03
prostate carcinoma · score 0.00
neoplasm · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-B9A6J9-F1	alphafold	PREDICTED	59.12	—

Amino-acid sequence (549 residues)

MDVVEVAGSW WAQEREDIIM KYEKGHRAGL PEDKGPKPFR SYNNNVDHLG IVHETELPPL TAREAKQIRR EISRKSKWVD MLGDWEKYKS SRKLIDRAYK GMPMNIRGPM WSVLLNTEEM KLKNPGRYQI MKEKGKRSSE HIQRIDRDVS GTLRKHIFFR DRYGTKQREL LHILLAYEEY NPEVGYCRDL SHIAALFLLY LPEEDAFWAL VQLLASERHS LQGFHSPNGG TVQGLQDQQE HVVATSQPKT MGHQDKKDLC GQCSPLGCLI RILIDGISLG LTLRLWDVYL VEGEQALMPI TRIAFKVQQK RLTKTSRCGP WARFCNRFVD TWARDEDTVL KHLRASMKKL TRKQGDLQPP AKPEQGSSAS RPVPASRGGK TLCKGDRQAP PGPPARFPRP IWSASPPRAP RSSTPCPGGA VREDTYPVGT QGVPSPALAQ GGPQGSWRFL QWNSMPRLPT DLDVEGPWFR HYDFRQSCWV RAISQEDQLA PCWQAEHPAE RVRSAFAAPS TDSDQGTPFR ARDEQPCAPT SGPCLCGLHL ESSQFPPGF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards