PTEN upstream open reading frame MP31 (MLDHR)

About PTEN upstream open reading frame MP31

PTEN upstream open reading frame MP31 (MLDHR) is a protein from Homo sapiens identified by UniProt accession C0HLV8, 31 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	PTEN upstream open reading frame MP31
UniProt accession	C0HLV8
Gene	MLDHR
Organism	Homo sapiens
Length	31 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

Cowden syndrome 1 · score 0.39
PTEN hamartoma tumor syndrome · score 0.20
Inherited cancer-predisposing syndrome · score 0.20
hereditary neoplastic syndrome · score 0.20
macrocephaly-autism syndrome · score 0.17
prostate carcinoma · score 0.17
prostate cancer · score 0.17
familial meningioma · score 0.17
glioma susceptibility 2 · score 0.17
Familial prostate cancer · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-C0HLV8-F1	alphafold	PREDICTED	84.85	—

Amino-acid sequence (31 residues)

MWRDSLCAAA GYALGAGTRL RSVLSSRKLQ P

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards