About Apical junction component 1 homolog
Apical junction component 1 homolog (AJM1) is a protein
from Homo sapiens identified by UniProt accession
C9J069, 976 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Apical junction component 1 homolog |
|---|
| UniProt accession | C9J069 |
|---|
| Gene | AJM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 976 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- infection · score 0.00
- infect · score 0.00
- sessile serrated polyp · score 0.00
- ulcerative colitis · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-C9J069-F1 | alphafold | PREDICTED | 52.68 | — |
Amino-acid sequence (976 residues)
MTRTDPPDLL VSTVYQDIKV ATPGPASKCS PCERSVARPA EPAPFNKRHC RSFDFLEALD GPAMETLPEP PPPESAVPRA RTREAEPRRR ARSKSAPRAP PGLTPAPASP PVLPRRGREA QRAARAEASP RREPAYPALR ALANELHPIK LQPQRGGPGR VAPLCAAAGR CAPPEPPAGP APHVRCRLDI KPDDAVLQHA TRGSRSCGPT EAAHWARPAP QFHGLTVPGP RHMALSRTPT PSDSYCADPR AFYCDGPLPG PRDYAERRSL PFTTPPGPTQ FFYTEEPQGF RGSFAASPGP TFDAYYPRPY PSEELSGPSP RRMGGYYAGE VRTFPIQEPP SRSYYGEAPR AYGLPYGPRY VPEEPRAHST ARPFYTEDFG RYRERDVLAR TYPHPRSSPA WADWGPRPYR TLQVVPPSDP DPLLASWHGG TGTSPPRLAT DSRHYSRSWD NILAPGPRRE DPLGRGRSYE NLLGREVREP RGVSPEGRRP PVVVNLSTSP RRYAALSLSE TSLTEKGRAG EGLGRNWYVT PEITITDNDL RATERPSARA WELPGGRTRP PPHAAPDGPT SGRQRSLEQL DELITDLVID SRPTAGQASE PAADCLGPQL RRLLDSRPAG SGAPALAPPR SPPASAGSAE EPAAPGEAAD ASPEPSADED DLMTCSNARC RRTETMFNAC LYFKSCHSCY TYYCSRLCRR EDWDAHKARC VYGRVGSVCR HVLQFCRDSG PVHRAFSRIA RVGFLSRGRG VLFLGFPSPG SADNFLRFGL EGLLLSPTYL SLRELATHAA PLGSYARELA AAGRLYEPAE CFLLSVSVAV GPGTAPPGTP ALPAPAPRSH GPTVRKFAKV ALAAGSPARP PPARSREPDM ETLILTPPPG TAGLDQDGEA GRRAREVAFI HIQRELRLRG VFLRHEFPRV YEQLCEFVEA NRRFTPTTIY PTDRRTGRPF MCMIMAASEP RALDWVASAN LLDDIM
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