Putative glycosyltransferase ALG1L2 (ALG1L2)

About Putative glycosyltransferase ALG1L2

Putative glycosyltransferase ALG1L2 (ALG1L2) is a protein from Homo sapiens identified by UniProt accession C9J202, 215 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Putative glycosyltransferase ALG1L2
UniProt accession	C9J202
Gene	ALG1L2
Organism	Homo sapiens
Length	215 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.12
autism · score 0.11
body height · score 0.06
neutrophil immunodeficiency syndrome · score 0.05
linear and whorled nevoid hypermelanosis · score 0.05
chronic myeloproliferative disorder · score 0.04
transient myeloproliferative syndrome · score 0.04
primary immunodeficiency syndrome due to p14 deficiency · score 0.04
chronic myelogenous leukemia · score 0.04
neutropenia, severe congenital, 1, autosomal dominant · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-C9J202-F1	alphafold	PREDICTED	76.95	—

Amino-acid sequence (215 residues)

MGATAGWAVT VYDKPASFFK EAPLDLQHRL FMKLGSTHSP FRARSEPEDP DTERSAFTER DSGSGLVTRL HERPALLVSS TSWTEFEQLT LDGQNLPSLV CVITGKGPLR EYYSRLIHQK HFQHIQVCIP WLEGRGLPPL LGSVDLDVCL DTSSSGLDLP MKVVDMFRCC LPACAVNFKC LHELVKHEEN RLVFEDSEEL AAQLQYFADA FLKLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards