About Testis-expressed protein 22
Testis-expressed protein 22 (TEX22) is a protein
from Homo sapiens identified by UniProt accession
C9J3V5, 150 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Testis-expressed protein 22 |
|---|
| UniProt accession | C9J3V5 |
|---|
| Gene | TEX22 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 150 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.39
- blood protein measurement · score 0.33
- testosterone measurement · score 0.17
- appendicular lean mass · score 0.07
- total blood protein measurement · score 0.07
- body height · score 0.06
- mean platelet volume · score 0.06
- diabetes mellitus · score 0.05
- gut microbiome measurement · score 0.05
- immunoglobulin isotype switching measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-C9J3V5-F1 | alphafold | PREDICTED | 61.23 | — |
Amino-acid sequence (150 residues)
MDSRKLSPRG KKLESHLSQE HRRPPLGLIA AWGQPSIQSS VQQGLQTQDW VCEPPERRRP GRRWSVSIDE RRRLATLGGR ERPGAAGTQL HCRDVVQMVA QLVSEDVDKD VLLPHPLRST ESTNAFQAFL ARSAPFWHNA TFEASRSPPS
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