Heat shock factor-binding protein 1-like protein 1…

About Heat shock factor-binding protein 1-like protein 1

Heat shock factor-binding protein 1-like protein 1 (HSBP1L1) is a protein from Homo sapiens identified by UniProt accession C9JCN9, 74 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Heat shock factor-binding protein 1-like protein 1
UniProt accession	C9JCN9
Gene	HSBP1L1
Organism	Homo sapiens
Length	74 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

aspartate aminotransferase measurement · score 0.24
self reported educational attainment · score 0.18
appendicular lean mass · score 0.07
schizophrenia · score 0.06
leukocyte count · score 0.05
myeloid white cell count · score 0.05
neutrophil count · score 0.04
response to isoquinoline alkaloid · score 0.04
monocyte count · score 0.03
isolated optic nerve hypoplasia · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-C9JCN9-F1	alphafold	PREDICTED	87.97	—

Amino-acid sequence (74 residues)

MDVRGPEAPG GRALRDAAEN LFQELQEHFQ ALTATLNLRM EEMGNRIEDL QKNVKDLMVQ AGIENSIKEQ MLKT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Heat shock factor-binding protein 1-like protein 1 (HSBP1L1)