About Proline-rich transmembrane protein 4
Proline-rich transmembrane protein 4 (PRRT4) is a protein
from Homo sapiens identified by UniProt accession
C9JH25, 899 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Proline-rich transmembrane protein 4 |
|---|
| UniProt accession | C9JH25 |
|---|
| Gene | PRRT4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 899 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- pelvic organ prolapse · score 0.02
- systemic lupus erythematosus · score 0.00
- acute myeloid leukemia · score 0.00
- cancer · score 0.00
- Sepsis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-C9JH25-F1 | alphafold | PREDICTED | 52.64 | — |
Amino-acid sequence (899 residues)
MARHGCLGLG LFCCVLFAAT VGPQPTPSIP GAPATTLTPV PQSEASMLSL NLGLNFKFHL RGPAAVWGSP VTETQPLSLG PGQEPGEEVA SGLRTDPLWE LLVGSSGNSL TEWGSTEGGS KPRASSLLPE STSRRSGPSD GPTAPYQPRR STVTWDTALM VTALPSSAPR PHQSELELKF DMALRAGAAP TLGHRTLPLL PSLRASLAEI AGRLGPFGFF GTTLSPLRNF SGLSPPGETT STSSASGVSG SLGFLGTTLS LPPYSLERKL SSPSPLDPAA SLSFASIATT SLDPTVPISG PDDLSPPASL GNPSGQPECG PGSCSVGELP EREGQPPEAP RPLFFLTLEA DWAEARARWG LAWEAHVYGV GALFGLVALL ALLALALLPW RCPPGAPCLA LLDLLLLSAG TTRAFPLFYD AYGHRDRLPA LAWLLLQDLP LPCLAAGLGL ACLLLARPRP PRCPTGLAAL LLLGLGLAAA AALGSAAHRP LRPLRLASRG LHAFLAAFLS GLLLALSCWG GRRRRAGAPL GGSGFKGATP LPQGRSPFAP RESWRRAART APVAGTFGLL SGALQGYEVL HALGYGGQSG LEGPWPWWAF QLGLRLGEVG VALPLALLGL YPALCSPRVP PRCWAKLFRL SPGHAAPLLP GGWVTGPPDK EPLGSAIARG DAELLQLCAL AGPGPDLLLQ GGGCRGFEGA AANPAPSPAS SPCSDYTVDF RPPSPINLRR SIEEALCSEA LLAPGLFQGP AFEDALPGLG LYRTASLGTG GRASERSGEA SGPAAPPELP SPGAWPAGSS VSSGSFCGLS RDSSSMLLCS SPDRPPRCPL VCVLSPPRPS GSSPSLPASG SYQALSPPSR DSPEPASELQ AEEALLQEQF LDACRQIDEL SVGSDTIDL
Explore Proline-rich transmembrane protein 4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets