BTB/POZ domain-containing protein 19 (BTBD19)

About BTB/POZ domain-containing protein 19

BTB/POZ domain-containing protein 19 (BTBD19) is a protein from Homo sapiens identified by UniProt accession C9JJ37, 291 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	BTB/POZ domain-containing protein 19
UniProt accession	C9JJ37
Gene	BTBD19
Organism	Homo sapiens
Length	291 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

low density lipoprotein cholesterol measurement · score 0.08
intraocular pressure measurement · score 0.04
platelet component distribution width · score 0.04
apolipoprotein B measurement · score 0.02
ependymoma · score 0.01
pancreatic ductal adenocarcinoma · score 0.01
myelodysplastic syndrome · score 0.01
tuberculosis · score 0.01
Sepsis · score 0.01
septic shock · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-C9JJ37-F1	alphafold	PREDICTED	91.84	—

Amino-acid sequence (291 residues)

MEPLGLVVHG KAEPFSAALR SLVNNPRYSD VCFVVGQERQ EVFAHRCLLA CRCNFFQRLL GTEPGPGVPS PVVLSTVPTE AFLAVLEFLY TNSVKLYRHS VLEVLTAAVE YGLEELRELC LQFVVKVLDV DLVCEALQVA VTFGLGQLQE RCVAFIEAHS QEALRTRGFL ELSAAALLPL LRSDKLCVDE AELVRAARSW ARVGAAVLER PVAEVAAPVV KELRLALLAP AELSALEEQN RQEPLIPVEQ IVEAWKCHAL RRGDEARGAP CRRRRGTLPR EHHRFLDLSF K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards