About Meiosis initiator protein
Meiosis initiator protein (MEIOSIN) is a protein
from Homo sapiens identified by UniProt accession
C9JSJ3, 638 residues long.
MolForge cross-references it against 0 known binders and
118 disease associations.
Target properties
| Protein name | Meiosis initiator protein |
|---|
| UniProt accession | C9JSJ3 |
|---|
| Gene | MEIOSIN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 638 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (118)
Diseases linked to this target (Open Targets).
- body height · score 0.13
- serum albumin measurement · score 0.13
- platelet count · score 0.11
- vitamin D measurement · score 0.09
- azoospermia · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- partial chromosome Y deletion · score 0.06
- coronary artery disease · score 0.06
- retinal vasculature measurement · score 0.06
- sex hormone-binding globulin measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-C9JSJ3-F1 | alphafold | PREDICTED | 51.38 | — |
Amino-acid sequence (638 residues)
MFGSSRYLGS SEQPRANSLG PSDRTLVLCS LVEGEDKVNP SEPHGLRMEE KWLLKGKLRN QRNQNKLLSP NKKQRKNHTS KLQELALLLP IALKTGTKKL TKKEILVHVL QYIQYLQRNI DAAKALFKCH ITTGEGGLAG LGQKPAWGPA RRRRHSTPSS SPSSQKSCLQ GACQKPRKKK LTQASESQTR TPKPRRSLAL NKPEKLVAPS PDQKGSGTGG TTTPPRCPDS CGHPRPASSS PPGDRKGGQS QLTLLDLAED TIHCDISSCW CQGSVQDDAP FPALLAQEDV ARIHFLNKTQ PHPRQKLVFY DSSEDVDKGS LDADPWLPAW TPENSPQGSP LFLGPPQIDV WSGTGHPSEI LGLSPSLFSS PGKLLPDEIL EDDMEYLTQA AFFEEVCLDL ESSPSAYTQE APQEKDTASK APKDPPESHS LHRSSVSLDH CYLSLSGNSK APSSSSSSSS SSSSSEDSDS EPLWKQREDM QANPVGTPGS SEEDEDTTWT PTRLASPLLA AEKKATKGQV ARAPVKPKEK KKGPCPPQMK KKCVNGFIMF CRMNRKQYIR SCPGTASTAA TKELAQLWRV MTQQERRPYC TKARRFSRQH NRIVKQDGSS SEAEDWETPK PFYQLLAEKA LPLPPHLQ
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