Ankyrin repeat domain-containing protein 63 (ANKRD63)

About Ankyrin repeat domain-containing protein 63

Ankyrin repeat domain-containing protein 63 (ANKRD63) is a protein from Homo sapiens identified by UniProt accession C9JTQ0, 380 residues long. MolForge cross-references it against 0 known binders and 1 disease associations.

Target properties

Protein name	Ankyrin repeat domain-containing protein 63
UniProt accession	C9JTQ0
Gene	ANKRD63
Organism	Homo sapiens
Length	380 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-C9JTQ0-F1	alphafold	PREDICTED	61.50	—

Amino-acid sequence (380 residues)

MLKPKDLCPR AGTRTFLEAM QAGKVHLARF VLDALDRSII DCRAEQGRTP LMVAVGLPDP ALRARFVRLL LEQGAAVNLR DERGRTALSL ACERGHLDAV QLLVQFSGDP EAADSAGNSP VMWAAACGHG AVLEFLVRSF RRLGLRLDRT NRAGLTALQL AAARGHGTCV QALTGPWGRA AAAAAARGSN SDSPPGRPAP AASPEHRRPS PRRLPRPLLA RFARAAGGHG GEAGSAGKNS GRHRAQGSER PELGRSMSLA LGAVTEEEAA RLRAGALMAL PNSPQSSGTG RWRSQEVLEG APPTLAQAPI GLSPHPEGGP GSGRLGLRRR STAPDIPSLV GEAPGPESGP ELEANALSVS VPGPNPWQAG TEAVVLRAQR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards