Protein PRAC2 (PRAC2)

About Protein PRAC2

Protein PRAC2 (PRAC2) is a protein from Homo sapiens identified by UniProt accession D3DTV9, 90 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Protein PRAC2
UniProt accession	D3DTV9
Gene	PRAC2
Organism	Homo sapiens
Length	90 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

appendicular lean mass · score 0.28
balding measurement · score 0.21
prostate carcinoma · score 0.17
restless legs syndrome · score 0.16
low density lipoprotein cholesterol measurement · score 0.10
total cholesterol measurement · score 0.10
systolic blood pressure · score 0.08
breast cancer · score 0.05
eosinophil percentage of leukocytes · score 0.04
neoplasm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-D3DTV9-F1	alphafold	PREDICTED	60.48	—

Amino-acid sequence (90 residues)

MDRRRMALRP GSRRPTAFFF HSRWLVPNLL AFFLGLSGAG PIHLPMPWPN GRRHRVLDPH TQLSTHEAPG RWKPVAPRTM KACPQVLLEW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards