Killer cell lectin-like receptor subfamily F member…

About Killer cell lectin-like receptor subfamily F member 2

Killer cell lectin-like receptor subfamily F member 2 (KLRF2) is a protein from Homo sapiens identified by UniProt accession D3W0D1, 207 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Killer cell lectin-like receptor subfamily F member 2
UniProt accession	D3W0D1
Gene	KLRF2
Organism	Homo sapiens
Length	207 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

neutrophil-to-lymphocyte ratio · score 0.25
platelet count · score 0.03
eosinophil count · score 0.03
platelet crit · score 0.02
psoriasis · score 0.02
Friedreich ataxia · score 0.00
skin disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-D3W0D1-F1	alphafold	PREDICTED	82.40	—

Amino-acid sequence (207 residues)

MENEDGYMTL SFKNRCKSKQ KSKDFSLYPQ YYCLLLIFGC IVILIFIMTG IDLKFWHKKM DFSQNVNVSS LSGHNYLCPN DWLLNEGKCY WFSTSFKTWK ESQRDCTQLQ AHLLVIQNLD ELEFIQNSLK PGHFGWIGLY VTFQGNLWMW IDEHFLVPEL FSVIGPTDDR SCAVITGNWV YSEDCSSTFK GICQRDAILT HNGTSGV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Killer cell lectin-like receptor subfamily F member 2 (KLRF2)