About Mucin-22
Mucin-22 (MUC22) is a protein
from Homo sapiens identified by UniProt accession
E2RYF6, 1773 residues long.
MolForge cross-references it against 0 known binders and
76 disease associations.
Target properties
| Protein name | Mucin-22 |
|---|
| UniProt accession | E2RYF6 |
|---|
| Gene | MUC22 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1773 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (76)
Diseases linked to this target (Open Targets).
- Graves disease · score 0.28
- prostate carcinoma · score 0.28
- blood protein measurement · score 0.28
- response to thioamide · score 0.27
- Drug-induced agranulocytosis · score 0.27
- cervical carcinoma · score 0.24
- unipolar depression · score 0.19
- psoriasis vulgaris · score 0.19
- Takayasu arteritis · score 0.18
- intraocular pressure change measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-E2RYF6-F1 | alphafold | PREDICTED | 67.45 | — |
Amino-acid sequence (1773 residues)
MRRGNISPAF WFLWLLLFGL LGPSSENTTA FTKGSDTTTA SITGSETTMA STMASTSALT TGSKITTDST TGSETTSAST MASTAAFTTG SETNTASTTD SGTTIASTRT FTTGSDTTTG STAGSETIVA STTVSGTTTT FTIASTTVPE TTMASSTTST AGSEKTMASS IISETTMAST TGSETATVST TGSETTTTST ASSEATKVST TGSETTTAST AGSETTTTST SMAGSEATTT STADSKVITA SSMSSETTVA PAAGSNTTTA STTGSETTTI LIKASETTTA STAGSETTTP SPTGSQTTIV SISGSEITTT STAGSENTTV SSAGSGTTTA SMAGSETTVS TAGSETTTVS ITGTETTMVS AMGSETTTNS TTSSETTVTS TAGSETTTVS TVGSETTTAY TADSETTAAS TTGSEMTTVF TAGSETITPS TAGSETTTVS TAGSETTTVS TTGSETTTAS TAHSETTAAS TMGSETTKVS TAGSETTVST AGSETTAAST EDSETNTAFT EDSKTTTAST TGFETTAAST TGSEPTMAST MGSETTMAST IGPETTKVST ASSEVTTVFA AGSETIRAST VGSETTTVST TGSETTTASI MGSETSTDST TGSETTTAST EGSETTTAST EGSEATTVST TGSETTTVSI TDSETTTTCT EGSEMTAVST TVFETTTAST EGSEITIAST SDSETTTAST EGSETTTVTT AGSETKTAYT TGSETTTASN TGLETTTVFT IGSDTTTAST EGSETTAVSA TGSEMTTVST EGSENTTVST TGSETTTVST TGLETTTTST EGSEMTTVST TGAETTTDST EGSGTTAAST AGSETTTVST ADSENTTAST ADSETTSAST TGSETTTAST TSSETTTAST EGSETTTVST TDSETTMVST TGSERTITST EGSETTTVSA TGSETTVSTE GSGTTTVSIT GSETTKVSTT GSETTTTSTE GSEITTASIT GSETTTASTE GSETTTASTE GSETTSASTT GSETTTASTT SSETTMASIM GSETTMASTI GSETTKVSTA SSKMTTVFTE NSETTIASTT ASETTTVSTA GSETIPASTA GSETTTTTST EGSETTTAST EGSETTTAST ESSETTTATT IGSETTTAST EGSETTTTST EGSETTTAST EGSEITTVST TGSETTTAST EGSETTTAST EGSELTTVST TGSETITVSA EGSETTTVTT MGSETTTAST AGSETTTVST AGSETTTASI EGSETTTVSS TGSETTTVST TGTETTITST EGSETTTVTT AGSETTAVYT TGSETTTTST EGSETTTVST TGSETTTAST ADLETTTVST SGSGTTTAST AGSETTTVYI TGSKTTTAST EGSEATTVST TSSETTTAST TGSEMTTVFT TVSETTTVST IGSEATTSSA AGSEATTTST EGSETTTAST AGSETTTAST AGSETTTAST SGSETNTACT TGSETSTPSS AGSETNTAFI IGSESTIAST ASLEPTATSL TGSETTTVSI TASGATAAST TVSSTTFVLT KATDVSIQPI TNTPMSGTRT TGTRLTASSS VTMAPGMDFT ASAASHTVPG IVLNTSGLGT STMGASSTTS AHGVRTTTGS TREPTSSTFQ ETGPVSMGTN TVSMSHTPTN VIKPSGYLQP WAIILISLAA VVAAVGLSVG LSFCLRNLFF PLRYCGIYYP HGHSHSLGLD LNLGLGSGTF HSLGNALVHG GELEMGHGGT HGFGYGVGHG LSHIHGDGYG VNHGGHYGHG GGH
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