Formiminotransferase N-terminal…

About Formiminotransferase N-terminal subdomain-containing protein

Formiminotransferase N-terminal subdomain-containing protein (FTCDNL1) is a protein from Homo sapiens identified by UniProt accession E5RQL4, 147 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Formiminotransferase N-terminal subdomain-containing protein
UniProt accession	E5RQL4
Gene	FTCDNL1
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.40
osteoporosis · score 0.31
insomnia · score 0.15
autism spectrum disorder · score 0.14
bipolar disorder · score 0.12
Red cell distribution width · score 0.12
attention deficit hyperactivity disorder · score 0.12
anorexia nervosa · score 0.11
self reported educational attainment · score 0.10
Cluster headache · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-E5RQL4-F1	alphafold	PREDICTED	77.09	—

Amino-acid sequence (147 residues)

MSSSRVGLRL AACLLNVSEA GRKYIVENIA KAALLDKNGK KHPQVSVLNI FSDQDYKRSV ITIATSVDKL GLAEDLVLHV PGCSVFLFGE ADLPEKRSLV QRRKQLGWFT RRDFSALQPD LGAAPSQRCG LTGSEHGFCF ALFFFFF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Formiminotransferase N-terminal subdomain-containing protein (FTCDNL1)