About Zinc finger protein 587B
Zinc finger protein 587B (ZNF587B) is a protein
from Homo sapiens identified by UniProt accession
E7ETH6, 402 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Zinc finger protein 587B |
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| UniProt accession | E7ETH6 |
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| Gene | ZNF587B |
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| Organism | Homo sapiens |
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| Length | 402 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.18
- sex hormone-binding globulin measurement · score 0.17
- neurodegenerative disease · score 0.16
- mean corpuscular volume · score 0.05
- allergic rhinitis · score 0.04
- neoplasm · score 0.03
- breast cancer · score 0.00
- axial length measurement · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-E7ETH6-F1 | alphafold | PREDICTED | 50.37 | — |
Amino-acid sequence (402 residues)
MAVVATLRLS AQGTVTFEDV AVKFTQEEWN LLSEAQRCLY RDVTLENLAL MSSLGCWCGV EDEAAPSKQS IYIQRETQVR TPVTGVSPKK AHPCEMCGPI LGDILHVADH QGTHHKQKLH RCEAWGNKLY DSGNFHQHQN EHIGEKPYRG SVEEALFVKR CKLHVSGESS VFSESGKDFL PRSGLLQQEA SHTGEKSNSK TECVSPFQCG GAHYSHGDSM KHFSTKHILS QHQRLLPREE CYVCCECGKS FSKYVSFSNH QRVHSGKRPY ECGECEKSFS QKSSLIQHQQ FHTGGKPYGC EECGKYFSLE GYLRRHQKVH AGKGPYECGE CGKSFSSNVN LKSHQRIHTG ERPYKCGECE KSFSRKPSLS YHQRFGRPRW VDHKDRKEFK TSLGNIVKSC LF
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