About Putative protein PTGES3L
Putative protein PTGES3L (PTGES3L) is a protein
from Homo sapiens identified by UniProt accession
E9PB15, 166 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Putative protein PTGES3L |
| UniProt accession | E9PB15 |
| Gene | PTGES3L |
| Organism | Homo sapiens |
| Length | 166 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- total blood protein measurement · score 0.14
- creatinine measurement · score 0.07
- body mass index · score 0.06
- lymphocyte percentage of leukocytes · score 0.05
- oral squamous cell carcinoma · score 0.01
- ulcerative colitis · score 0.00
- triple-negative breast cancer · score 0.00
- acquired idiopathic inflammatory myopathy · score 0.00
- arthrogryposis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-E9PB15-F1 | alphafold | PREDICTED | 72.79 | — |
Amino-acid sequence (166 residues)
MFSLPLNCSP DHIRRGSCWG RPQDLKIAAP AWNSKCHPGA GAAMARQHAR TLWYDRPRYV FMEFCVEDST DVHVLIEDHR IVFSCKNADG VELYNEIEFY AKVNSKPVWL SVDFDNWRDW EGDEEMELAH VEHYAELLKK VSTKRPPPAM DDLDDDSDSA DDATSN
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