About Nuclear pore complex-interacting protein family member A2
Nuclear pore complex-interacting protein family member A2 (NPIPA2) is a protein
from Homo sapiens identified by UniProt accession
E9PIF3, 369 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member A2 |
|---|
| UniProt accession | E9PIF3 |
|---|
| Gene | NPIPA2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 369 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- diabetic nephropathy · score 0.06
- brain aneurysm · score 0.02
- visual perception measurement · score 0.02
- low density lipoprotein cholesterol measurement · score 0.02
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-E9PIF3-F1 | alphafold | PREDICTED | 52.25 | — |
Amino-acid sequence (369 residues)
MVKLSIVLTP RFLSHDQGQL TKELQQHVKS VTCPCEYLRK VINTLADHRH RGTDFGGSPW LLIITVFLRS YKFAISLCTS YLCVSFLKTI FPSQNGHDGS TDVQQRARRS NRRRQEGIKI VLEDIFTLWR QVETKVRAKI CKMKVTTKVN RHDKINGKRK TAKEHLRKLS MKEREHGEKE RQVSEAEENG KLDMKEIHTY MEMFQRAQAL RRRAEDYYRC KITPSARKPL CNRVRMAAAE HRHSSGLPYW PYLTAETLKN RMGHQPPPPT QQHSIIDNSL SLKTPPECLL TPLPPSALPS ADDNLKTPAE CLLYPLPPSA DDNLKTPPEC LLTPLPPSAP PSADDNLKTP PKCVCSLPFH PQRMIISRN
Explore Nuclear pore complex-interacting protein family member A2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets