About Ubiquitin-associated protein 1-like
Ubiquitin-associated protein 1-like (UBAP1L) is a protein
from Homo sapiens identified by UniProt accession
F5GYI3, 381 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Ubiquitin-associated protein 1-like |
|---|
| UniProt accession | F5GYI3 |
|---|
| Gene | UBAP1L |
|---|
| Organism | Homo sapiens |
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| Length | 381 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- Cone rod dystrophy · score 0.19
- cone-rod dystrophy · score 0.18
- retinitis pigmentosa · score 0.18
- acute myocardial infarction · score 0.01
- respiratory distress syndrome in premature infants · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-F5GYI3-F1 | alphafold | PREDICTED | 65.43 | — |
Amino-acid sequence (381 residues)
MNALDGVPFK LPKGFVIGTE PLPGPELSVP ACGEVLLGSM HDFSLERTAL FWVEAAGQGP SPYQCGDPGT ASAPPAWLLL VSPEHGLAPA PTTIRDPEAG HQERPEEEGE DEAEASSGSE EEPAPSSLQP GSPASPGPGR RLCSLDVLRG VRLELAGARR RLSEGKLVSR PRALLHGLRG HRALSLCPSP AQSPRSASPP GPAPQHPAAP ASPPRPSTAG AIPPLRSHKP TVASLSPYTC LPPLGGAPQP LNPHKSHPDT AADLLSALSQ EEQDLIGPVV ALGYPLRRAI IALQKTGRQS LSQFLSYLSA CDRLLRQGYE EGLVDEAMEM FQFSESQAGE FLRLWEQFSD MGFQQDRIKE VLLVHGNRRE QALEELVACA Q
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