About Nuclear pore complex-interacting protein family member A3
Nuclear pore complex-interacting protein family member A3 (NPIPA3) is a protein
from Homo sapiens identified by UniProt accession
F8WFD2, 350 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member A3 |
|---|
| UniProt accession | F8WFD2 |
|---|
| Gene | NPIPA3 |
|---|
| Organism | Homo sapiens |
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| Length | 350 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- brain aneurysm · score 0.02
- visual perception measurement · score 0.02
- BMI-adjusted waist circumference · score 0.02
- diastolic blood pressure · score 0.02
- age-related macular degeneration · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-F8WFD2-F1 | alphafold | PREDICTED | 51.54 | — |
Amino-acid sequence (350 residues)
MFCCLGYEWL SGGCKTWHSA WVINTLADHR HRGTDFGGSP WLLIITVFLR SYKFAISLCT SYLCVSFLKT IFPSQNGHDG STDVQQRARR SNRRRQEGIK IVLEDIFTLW RQVETKVRAK ICKMKVTTKV NRHDKINGKR KTAKEHLRKL SMKEREHGEK ERQVSEAEEN GKLDMKEIHT YMEMFQRAQA LRRRAEDYYR CKITPSARKP LCNRVRMAAA EHRHSSGLPY WPYLTAETLK NRMGHQPPPP TQQHSIIDNS LSLKTPPECL LTPLPPSALP SADDNLKTPA ECLLYPLPPS ADDNLKTPPE CLLTPLPPSA PPSVDDNLKT PPKCVCSLPF HPQRMIISRN
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