Thiosulfate sulfurtransferase/rhodanese-like…

About Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3

Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 (TSTD3) is a protein from Homo sapiens identified by UniProt accession H0UI37, 97 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3
UniProt accession	H0UI37
Gene	TSTD3
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

age at menarche · score 0.19
body height · score 0.18
testosterone measurement · score 0.17
enuresis · score 0.13
brain measurement · score 0.11
cerebellar volume measurement · score 0.10
puberty onset measurement · score 0.07
HbA1c measurement · score 0.07
daytime rest measurement · score 0.06
age at voice drop · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-H0UI37-F1	alphafold	PREDICTED	83.67	—

Amino-acid sequence (97 residues)

MKIEKCGWSE GLTSIKGNCH NFYTAISKDV TYKELKNLLN SKNIMLIDVR EIWEILEYQK IPESINVPLD EVGEALQMNP RDFKEKYNEV KPSKSDS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 (TSTD3)