About Protein FAM72C
Protein FAM72C (FAM72C) is a protein
from Homo sapiens identified by UniProt accession
H0Y354, 149 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Protein FAM72C |
|---|
| UniProt accession | H0Y354 |
|---|
| Gene | FAM72C |
|---|
| Organism | Homo sapiens |
|---|
| Length | 149 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- atopic eczema · score 0.12
- optic cup area measurement · score 0.11
- familial juvenile hyperuricemic nephropathy type 1 · score 0.06
- common variable immunodeficiency · score 0.05
- combined immunodeficiency with skin granulomas · score 0.05
- BENTA disease · score 0.05
- multicystic dysplastic kidney · score 0.05
- karyomegalic interstitial nephritis · score 0.04
- severe combined immunodeficiency due to CTPS1 deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-H0Y354-F1 | alphafold | PREDICTED | 85.37 | — |
Amino-acid sequence (149 residues)
MSTNICSFKD RCVSILCCKF CKQVLSSRGM KAVLLADTEI DLFSTDIPPT NAVDFTGRCY FTKICKCKLK DIACLKCGNI VVYHVIVPCS SCLLSCNNRH FWMFHSQAVY DINRLDSTGV NVLLRGNLPE IEESTDEDVL NISAEECIR
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