About MKRN2 opposite strand protein
MKRN2 opposite strand protein (MKRN2OS) is a protein
from Homo sapiens identified by UniProt accession
H3BPM6, 223 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | MKRN2 opposite strand protein |
|---|
| UniProt accession | H3BPM6 |
|---|
| Gene | MKRN2OS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 223 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- cystatin C measurement · score 0.27
- high density lipoprotein cholesterol measurement · score 0.27
- Red cell distribution width · score 0.27
- hemoglobin measurement · score 0.25
- hypertension · score 0.25
- apolipoprotein A 1 measurement · score 0.24
- body height · score 0.21
- erythrocyte count · score 0.19
- hair colour measurement · score 0.17
- eosinophil count · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-H3BPM6-F1 | alphafold | PREDICTED | 89.64 | — |
Amino-acid sequence (223 residues)
MHCAEAGKAL IKFNHCEKYI YSFSVPQCCP LCQQDLGSRK LEDAPVSIAN PFTNGHQEKC SFLLRPTQGT FLREYDGRSD LHVGITNTNG VVYNYSAHGV QRDGEGWEES ISIPLLQPNM YGMMEQWDKY LEDFSTSGAW LPHRYEDNHH NCYSYALTFI NCVLMAEGRQ QLDKGEFTEK YVVPRTRLAS KFITLYRAIR EHGFYVTDCP QQQAQPPEGG GLC
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