Golgin subfamily A member 8M (GOLGA8M)

About Golgin subfamily A member 8M

Golgin subfamily A member 8M (GOLGA8M) is a protein from Homo sapiens identified by UniProt accession H3BSY2, 632 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Golgin subfamily A member 8M
UniProt accession	H3BSY2
Gene	GOLGA8M
Organism	Homo sapiens
Length	632 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

hair color · score 0.34
hair colour measurement · score 0.20
hepatocellular carcinoma · score 0.01
neoplasm · score 0.00
cholangiocarcinoma · score 0.00
myelodysplastic syndrome · score 0.00
viral disease · score 0.00
autoimmune disease · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-H3BSY2-F1	alphafold	PREDICTED	66.06	—

Amino-acid sequence (632 residues)

MAEETQHNKL AAAKKKLKEY WQKNSPRVPA GANRNRKTNG SIPQTATSGG CQPPGDSATG FHREGPTSSA TLKDLESPCQ ERAVVLDSRS VEISQLKNTI KSLKQQKKQV EHQLEEEKKA NNKKQKAKRV LEVQLQTLNI QKEELNTDLY HMKRSLRYFE EKSKDLAVRL QHSLQRKGEL ESVLSDVMAT QKKKANQLSS PSKAGTEWKL EQSMREEALL KVQLTQLKES FQQVQLERDE YSEHLKGERA RWQQRMRKMS QEICTLKKEK QQDMRRVEKL ERSLSKLKNQ MAEPLPPEPP AVPSEVELQH LRKELERVAG ELQAQVKNNQ RISLLNQRQE ERIREQEERL RKQEERIQEQ HKSLQQLAKP QSVFEEPNNE NKSTLQLEQQ VKELQEKLGE EHLEAASQQN QQLTAQLSLM ALPGEGHGGE HLDSEGEEAP QPMPSVPEDP ESREAMSSFM DHLEEKADLS ELVKKQELRF IQYWQERCHQ KIHHLLSEPG GRAKDAALGG GHHQAGAQGG DEGEAAGAAA DGIAAYSNYN NGHRKFLAAA HNSADEPGPG APAPQELGAA DKHGDLCEVS LTSSAQGEAR EDPLLDKPTA QPIVQDHQEH PGLGSNCCVP FFCWAWLPRR RR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards