Testis-expressed protein 46 (TEX46)

About Testis-expressed protein 46

Testis-expressed protein 46 (TEX46) is a protein from Homo sapiens identified by UniProt accession H3BTG2, 121 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.

Target properties

Protein name	Testis-expressed protein 46
UniProt accession	H3BTG2
Gene	TEX46
Organism	Homo sapiens
Length	121 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (83)

Diseases linked to this target (Open Targets).

brain measurement · score 0.14
body fat percentage · score 0.14
cortical surface area measurement · score 0.13
fat body mass · score 0.12
appendicular lean mass · score 0.11
body mass index · score 0.11
serum gamma-glutamyl transferase measurement · score 0.11
lean body mass · score 0.10
neoplasm · score 0.10
body weight · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-H3BTG2-F1	alphafold	PREDICTED	67.84	—

Amino-acid sequence (121 residues)

MSLHGILASA GTIGAVAAWL MSYKPALFGF LFLLLLLSNW LVKYEHKLTL PEPQQDEILQ RLLFSEMKMK VLENQMFIIW NKMNHHGRSS RHRNFPMKKH RMRRHESICP TLSDCTSSSP S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards