About Transforming growth factor-beta receptor type 3-like protein
Transforming growth factor-beta receptor type 3-like protein (TGFBR3L) is a protein
from Homo sapiens identified by UniProt accession
H3BV60, 292 residues long.
MolForge cross-references it against 0 known binders and
76 disease associations.
Target properties
| Protein name | Transforming growth factor-beta receptor type 3-like protein |
|---|
| UniProt accession | H3BV60 |
|---|
| Gene | TGFBR3L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 292 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (76)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.19
- functional brain measurement · score 0.09
- neoplasm · score 0.09
- appendicular lean mass · score 0.08
- primary ovarian insufficiency · score 0.08
- 46,XX gonadal dysgenesis · score 0.07
- high density lipoprotein cholesterol measurement · score 0.07
- serum alanine aminotransferase measurement · score 0.07
- lean body mass · score 0.07
- type 2 diabetes mellitus · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-H3BV60-F1 | alphafold | PREDICTED | 72.57 | — |
Amino-acid sequence (292 residues)
MLGTVLLLAL LPGITTLPSG PPAPPFPAAP GPWLRRPLFS LKLSDTEDVF PRRAGPLEVP ADSRVFVQAA LARPSPRWGL ALHRCSVTPS SRPAPGPALA LLREGCPADT SVAFPPPPPP SPGAARPARF SFRLRPVFNA SVQFLHCQLS RCRRLRGVRR APAPLTPPPP PPPSRCLPQD EACADTGSGS AEGLAADGPH LHTLTQPIVV TVPRPPPRPP KSVPGRAVRP EPPAPAPAAL EPAPVVALVL AAFVLGAALA AGLGLVCAHS APHAPGPPAR ASPSGPQPRR SQ
Explore Transforming growth factor-beta receptor type 3-like protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets