Claudin-34 (CLDN34)

About Claudin-34

Claudin-34 (CLDN34) is a protein from Homo sapiens identified by UniProt accession H7C241, 214 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Claudin-34
UniProt accession	H7C241
Gene	CLDN34
Organism	Homo sapiens
Length	214 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

pseudohypoaldosteronism type 2B · score 0.04
pseudohypoaldosteronism type 2D · score 0.04
pseudohypoaldosteronism type 2E · score 0.03
gastric carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-H7C241-F1	alphafold	PREDICTED	86.45	—

Amino-acid sequence (214 residues)

MVWFCNSADC QFSVFALTTI GWILSSTSTG LVEWRIWYMK DTSLYPPGIA CVGIFRVCIY RRRTNSTTTK FCYRYSYQDT FLPFEISMAQ RFLLTASIFG FFGRAFNMFA LRNMSMRMFE EDTYNSFVVS GILNIAAGVF NLIAVLQNYD AVINSQGITF LPSLQMPFKP DVQEVGTAIQ VAGIGVLPML LTGMFSLFYK CPPYGQVHPG ISEM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards