UBX domain-containing protein 8 (UBXN8)

About UBX domain-containing protein 8

UBX domain-containing protein 8 (UBXN8) is a protein from Homo sapiens identified by UniProt accession O00124, 270 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	UBX domain-containing protein 8
UniProt accession	O00124
Gene	UBXN8
Organism	Homo sapiens
Length	270 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

acute myeloid leukemia · score 0.07
neoplasm · score 0.02
cancer · score 0.01
Anemia · score 0.01
hepatocellular carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00124-F1	alphafold	PREDICTED	77.08	—

Amino-acid sequence (270 residues)

MASRGVVGIF FLSAVPLVCL ELRRGIPDIG IKDFLLLCGR ILLLLALLTL IISVTTSWLN SFKSPQVYLK EEEEKNEKRQ KLVRKKQQEA QGEKASRYIE NVLKPHQEMK LRKLEERFYQ MTGEAWKLSS GHKLGGDEGT SQTSFETSNR EAAKSQNLPK PLTEFPSPAE QPTCKEIPDL PEEPSQTAEE VVTVALRCPS GNVLRRRFLK SYSSQVLFDW MTRIGYHISL YSLSTSFPRR PLAVEGGQSL EDIGITVDTV LILEEKEQTN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards