C-C motif chemokine 24 (CCL24)

About C-C motif chemokine 24

C-C motif chemokine 24 (CCL24) is a protein from Homo sapiens identified by UniProt accession O00175, 119 residues long. MolForge cross-references it against 0 known binders and 217 disease associations.

Target properties

Protein name	C-C motif chemokine 24
UniProt accession	O00175
Gene	CCL24
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (217)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.47
eosinophil percentage of leukocytes · score 0.43
eosinophil percentage of granulocytes · score 0.36
sum of eosinophil and basophil counts · score 0.34
blood protein measurement · score 0.34
basophil count · score 0.32
neutrophil percentage of granulocytes · score 0.28
sarcoidosis · score 0.28
basophil percentage of leukocytes · score 0.25
CCL24 measurement · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00175-F1	alphafold	PREDICTED	82.12	—

Amino-acid sequence (119 residues)

MAGLMTIVTS LLFLGVCAHH IIPTGSVVIP SPCCMFFVSK RIPENRVVSY QLSSRSTCLK AGVIFTTKKG QQFCGDPKQE WVQRYMKNLD AKQKKASPRA RAVAVKGPVQ RYPGNQTTC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards