Rho-related GTP-binding protein RhoD (RHOD)

About Rho-related GTP-binding protein RhoD

Rho-related GTP-binding protein RhoD (RHOD) is a protein from Homo sapiens identified by UniProt accession O00212, 210 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Rho-related GTP-binding protein RhoD
UniProt accession	O00212
Gene	RHOD
Organism	Homo sapiens
Length	210 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00212-F1	alphafold	PREDICTED	89.24	—

Amino-acid sequence (210 residues)

MTAAQAAGEE APPGVRSVKV VLVGDGGCGK TSLLMVFADG AFPESYTPTV FERYMVNLQV KGKPVHLHIW DTAGQDDYDR LRPLFYPDAS VLLLCFDVTS PNSFDNIFNR WYPEVNHFCK KVPIIVVGCK TDLRKDKSLV NKLRRNGLEP VTYHRGQEMA RSVGAVAYLE CSARLHDNVH AVFQEAAEVA LSSRGRNFWR RITQGFCVVT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards