26S proteasome non-ATPase regulatory subunit 9 (PSMD9)

Homo sapiens — UniProt O00233

Gene: PSMD9Homo sapiensSwissProt reviewed

About 26S proteasome non-ATPase regulatory subunit 9

26S proteasome non-ATPase regulatory subunit 9 (PSMD9) is a protein from Homo sapiens identified by UniProt accession O00233, 223 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name26S proteasome non-ATPase regulatory subunit 9
UniProt accessionO00233
GenePSMD9
OrganismHomo sapiens
Length223 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (62)

Diseases linked to this target (Open Targets).

  • HIV infection · score 0.46
  • urinary metabolite measurement · score 0.31
  • breast adenocarcinoma · score 0.30
  • appendicular lean mass · score 0.23
  • serum metabolite measurement · score 0.20
  • cognitive function measurement · score 0.20
  • self reported educational attainment · score 0.20
  • mean corpuscular volume · score 0.18
  • body height · score 0.15
  • lean body mass · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-O00233-F1alphafoldPREDICTED83.02—

Amino-acid sequence (223 residues)

MSDEEARQSG GSSQAGVVTV SDVQELMRRK EEIEAQIKAN YDVLESQKGI GMNEPLVDCE GYPRSDVDLY QVRTARHNII CLQNDHKAVM KQVEEALHQL HARDKEKQAR DMAEAHKEAM SRKLGQSESQ GPPRAFAKVN SISPGSPASI AGLQVDDEIV EFGSVNTQNF QSLHNIGSVV QHSEGKPLNV TVIRRGEKHQ LRLVPTRWAG KGLLGCNIIP LQR

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Quick facts

UniProtO00233
GenePSMD9
OrganismHomo sapiens
Length223
Binders0
Diseases62
View on UniProt