Copper transport protein ATOX1 (ATOX1)

About Copper transport protein ATOX1

Copper transport protein ATOX1 (ATOX1) is a protein from Homo sapiens identified by UniProt accession O00244, 68 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.

Target properties

Protein name	Copper transport protein ATOX1
UniProt accession	O00244
Gene	ATOX1
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (83)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
systolic blood pressure change measurement · score 0.33
Red cell distribution width · score 0.31
creatinine measurement · score 0.30
glomerular filtration rate · score 0.28
cortical surface area measurement · score 0.25
body mass index · score 0.25
cortical thickness · score 0.23
brain measurement · score 0.20
platelet component distribution width · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00244-F1	alphafold	PREDICTED	97.67	—

Amino-acid sequence (68 residues)

MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards