About Putative P2Y purinoceptor 10
Putative P2Y purinoceptor 10 (P2RY10) is a protein
from Homo sapiens identified by UniProt accession
O00398, 339 residues long.
MolForge cross-references it against 0 known binders and
46 disease associations.
Target properties
| Protein name | Putative P2Y purinoceptor 10 |
|---|
| UniProt accession | O00398 |
|---|
| Gene | P2RY10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 339 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (46)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.32
- glioblastoma multiforme · score 0.25
- ovarian cancer · score 0.24
- breast adenocarcinoma · score 0.24
- cutaneous melanoma · score 0.13
- neuroblastoma · score 0.11
- birth weight · score 0.10
- prostate adenocarcinoma · score 0.10
- Varicose veins · score 0.05
- Sepsis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O00398-F1 | alphafold | PREDICTED | 83.84 | — |
Amino-acid sequence (339 residues)
MANLDKYTET FKMGSNSTST AEIYCNVTNV KFQYSLYATT YILIFIPGLL ANSAALWVLC RFISKKNKAI IFMINLSVAD LAHVLSLPLR IYYYISHHWP FQRALCLLCF YLKYLNMYAS ICFLTCISLQ RCFFLLKPFR ARDWKRRYDV GISAAIWIVV GTACLPFPIL RSTDLNNNKS CFADLGYKQM NAVALVGMIT VAELAGFVIP VIIIAWCTWK TTISLRQPPM AFQGISERQK ALRMVFMCAA VFFICFTPYH INFIFYTMVK ETIISSCPVV RIALYFHPFC LCLASLCCLL DPILYYFMAS EFRDQLSRHG SSVTRSRLMS KESGSSMIG
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