Zinc finger protein 593 (ZNF593)

About Zinc finger protein 593

Zinc finger protein 593 (ZNF593) is a protein from Homo sapiens identified by UniProt accession O00488, 134 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Zinc finger protein 593
UniProt accession	O00488
Gene	ZNF593
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
heel bone mineral density · score 0.16
blood phosphate measurement · score 0.12
mean corpuscular volume · score 0.06
mean reticulocyte volume · score 0.05
diabetic cardiomyopathy · score 0.05
diabetes mellitus · score 0.05
wrist fracture · score 0.05
hypertrophic cardiomyopathy · score 0.03
hypertrophic cardiomyopathy 6 · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00488-F1	alphafold	PREDICTED	76.65	—

Amino-acid sequence (134 residues)

MGRSRRTGAH RAHSLARQMK AKRRRPDLDE IHRELRPQGS ARPQPDPNAE FDPDLPGGGL HRCLACARYF IDSTNLKTHF RSKDHKKRLK QLSVEPYSQE EAERAAGMGS YVPPRRLAVP TEVSTEVPEM DTST

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards