Receptor-binding cancer antigen expressed on SiSo…

About Receptor-binding cancer antigen expressed on SiSo cells

Receptor-binding cancer antigen expressed on SiSo cells (EBAG9) is a protein from Homo sapiens identified by UniProt accession O00559, 213 residues long. MolForge cross-references it against 0 known binders and 190 disease associations.

Target properties

Protein name	Receptor-binding cancer antigen expressed on SiSo cells
UniProt accession	O00559
Gene	EBAG9
Organism	Homo sapiens
Length	213 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (190)

Diseases linked to this target (Open Targets).

neoplasm · score 0.11
female infertility · score 0.10
oral squamous cell carcinoma · score 0.08
cancer · score 0.08
isolated agammaglobulinemia · score 0.07
common variable immunodeficiency · score 0.07
Chronic mucocutaneous candidosis · score 0.07
cortical thickness · score 0.06
cortical surface area measurement · score 0.06
immunodeficiency 18 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00559-F1	alphafold	PREDICTED	65.91	—

Amino-acid sequence (213 residues)

MAITQFRLFK FCTCLATVFS FLKRLICRSG RGRKLSGDQI TLPTTVDYSS VPKQTDVEEW TSWDEDAPTS VKIEGGNGNV ATQQNSLEQL EPDYFKDMTP TIRKTQKIVI KKREPLNFGI PDGSTGFSSR LAATQDLPFI HQSSELGDLD TWQENTNAWE EEEDAAWQAE EVLRQQKLAD REKRAAEQQR KKMEKEAQRL MKKEQNKIGV KLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Receptor-binding cancer antigen expressed on SiSo cells (EBAG9)