About Syntenin-1
Syntenin-1 (SDCBP) is a protein
from Homo sapiens identified by UniProt accession
O00560, 298 residues long.
MolForge cross-references it against 0 known binders and
158 disease associations.
Target properties
| Protein name | Syntenin-1 |
|---|
| UniProt accession | O00560 |
|---|
| Gene | SDCBP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 298 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (158)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.41
- aspartate aminotransferase measurement · score 0.39
- monocyte count · score 0.38
- lymphocyte count · score 0.34
- monocyte percentage of leukocytes · score 0.27
- testosterone measurement · score 0.25
- neurodegenerative disease · score 0.24
- basophil count · score 0.24
- breast adenocarcinoma · score 0.18
- bilirubin measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O00560-F1 | alphafold | PREDICTED | 83.02 | — |
Amino-acid sequence (298 residues)
MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS LNEEEIRANV AVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE INGQNVIGLK DSQIADILST SGTVVTITIM PAFIFEHIIK RMAPSIMKSL MDHTIPEV
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