About Ficolin-1
Ficolin-1 (FCN1) is a protein
from Homo sapiens identified by UniProt accession
O00602, 326 residues long.
MolForge cross-references it against 0 known binders and
194 disease associations.
Target properties
| Protein name | Ficolin-1 |
|---|
| UniProt accession | O00602 |
|---|
| Gene | FCN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 326 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (194)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.42
- leukocyte count · score 0.39
- blood protein measurement · score 0.39
- myeloid white cell count · score 0.36
- neurodegenerative disease · score 0.35
- ficolin-1 measurement · score 0.30
- neutrophil percentage of leukocytes · score 0.29
- ficolin-2 measurement · score 0.24
- lymphocyte percentage of leukocytes · score 0.14
- cutaneous melanoma · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O00602-F1 | alphafold | PREDICTED | 84.93 | — |
Amino-acid sequence (326 residues)
MELSGATMAR GLAVLLVLFL HIKNLPAQAA DTCPEVKVVG LEGSDKLTIL RGCPGLPGAP GPKGEAGVIG ERGERGLPGA PGKAGPVGPK GDRGEKGMRG EKGDAGQSQS CATGPRNCKD LLDRGYFLSG WHTIYLPDCR PLTVLCDMDT DGGGWTVFQR RMDGSVDFYR DWAAYKQGFG SQLGEFWLGN DNIHALTAQG SSELRVDLVD FEGNHQFAKY KSFKVADEAE KYKLVLGAFV GGSAGNSLTG HNNNFFSTKD QDNDVSSSNC AEKFQGAWWY ADCHASNLNG LYLMGPHESY ANGINWSAAK GYKYSYKVSE MKVRPA
Explore Ficolin-1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets