About Sodium-dependent phosphate transport protein 3
Sodium-dependent phosphate transport protein 3 (SLC17A2) is a protein
from Homo sapiens identified by UniProt accession
O00624, 439 residues long.
MolForge cross-references it against 0 known binders and
127 disease associations.
Target properties
| Protein name | Sodium-dependent phosphate transport protein 3 |
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| UniProt accession | O00624 |
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| Gene | SLC17A2 |
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| Organism | Homo sapiens |
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| Length | 439 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (127)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.36
- ACPA-positive rheumatoid arthritis · score 0.31
- body height · score 0.29
- systemic lupus erythematosus · score 0.23
- mean corpuscular volume · score 0.22
- testosterone measurement · score 0.20
- BMI-adjusted waist-hip ratio · score 0.17
- hemoglobin measurement · score 0.16
- blood protein measurement · score 0.14
- eosinophil percentage of leukocytes · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O00624-F1 | alphafold | PREDICTED | 83.14 | — |
Amino-acid sequence (439 residues)
MDGKPATRKG PDFCSLRYGL ALIMHFSNFT MITQRVSLSI AIIAMVNTTQ QQGLSNASTE GPVADAFNNS SISIKEFDTK ASVYQWSPET QGIIFSSINY GIILTLIPSG YLAGIFGAKK MLGAGLLISS LLTLFTPLAA DFGVILVIMV RTVQGMAQGM AWTGQFTIWA KWAPPLERSK LTTIAGSGSA FGSFIILCVG GLISQALSWP FIFYIFGSTG CVCCLLWFTV IYDDPMHHPC ISVREKEHIL SSLAQQPSSP GRAVPIKAMV TCLPLWAIFL GFFSHFWLCT IILTYLPTYI STLLHVNIRD SGVLSSLPFI AAASCTILGG QLADFLLSRN LLRLITVRKL FSSLGLLLPS ICAVALPFVA SSYVITIILL ILIPGTSNLC DSGFIINTLD IAPRYASFLM GISRGFGLIA GIISSTATGF LISQVGPVY
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