C-C motif chemokine 22 (CCL22)

About C-C motif chemokine 22

C-C motif chemokine 22 (CCL22) is a protein from Homo sapiens identified by UniProt accession O00626, 93 residues long. MolForge cross-references it against 0 known binders and 383 disease associations.

Target properties

Protein name	C-C motif chemokine 22
UniProt accession	O00626
Gene	CCL22
Organism	Homo sapiens
Length	93 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (383)

Diseases linked to this target (Open Targets).

asthma · score 0.24
systemic lupus erythematosus · score 0.21
blood protein measurement · score 0.18
red blood cell density measurement · score 0.12
hematocrit · score 0.12
neoplasm · score 0.11
esophageal squamous cell carcinoma · score 0.10
gonorrhea · score 0.08
COVID-19 · score 0.08
Cutaneous T-cell lymphoma · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O00626-F1	alphafold	PREDICTED	87.41	—

Amino-acid sequence (93 residues)

MDRLQTALLV VLVLLAVALQ ATEAGPYGAN MEDSVCCRDY VRYRLPLRVV KHFYWTSDSC PRPGVVLLTF RDKEICADPR VPWVKMILNK LSQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards