About Phospholipid transfer protein C2CD2L
Phospholipid transfer protein C2CD2L (C2CD2L) is a protein
from Homo sapiens identified by UniProt accession
O14523, 706 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Phospholipid transfer protein C2CD2L |
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| UniProt accession | O14523 |
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| Gene | C2CD2L |
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| Organism | Homo sapiens |
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| Length | 706 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- serum gamma-glutamyl transferase measurement · score 0.16
- high density lipoprotein cholesterol measurement · score 0.12
- mean corpuscular hemoglobin concentration · score 0.09
- mean corpuscular volume · score 0.08
- lymphocyte percentage of leukocytes · score 0.08
- creatinine measurement · score 0.06
- lymphocyte count · score 0.06
- benign adult familial myoclonic epilepsy · score 0.06
- glomerular filtration rate · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14523-F1 | alphafold | PREDICTED | 63.94 | — |
Amino-acid sequence (706 residues)
MDPGWGQRDV GWAALLILFA ASLLTVFAWL LQYARGLWLA RARGDRGPGP ALAGEPAGSL RELGVWRSLL RLRATRAGAA EEPGVRGLLA SLFAFKSFRE NWQRAWVRAL NEQACRNGSS IQIAFEEVPQ LPPRASISHV TCVDQSEHTM VLRCQLSAEE VRFPVSVTQQ SPAAVSMETY HVTLTLPPTQ LEVNLEEIPG EGLLISWAFT DRPDLSLTVL PKLQARERGE EQVELSTIEE LIKDAIVSTQ PAMMVNLRAC SAPGGLVPSE KPPMMPQAQP AIPRPNRLFL RQLRASHLGN ELEGTEELCC VAELDNPMQQ KWTKPARAGS EVEWTEDLAL DLGPQSRELT LKVLRSSSCG DTELLGQATL PVGSPSRPLS RRQLCPLTPG PGKALGPAAT MAVELHYEEG SPRNLGTPTS STPRPSITPT KKIELDRTIM PDGTIVTTVT TVQSRPRIDG KLDSPSRSPS KVEVTEKTTT VLSESSGPSN TSHSSSRDSH LSNGLDPVAE TAIRQLTEPS GRVAKKTPTK RSTLIISGVS KVPIAQDELA LSLGYAASLE ASVQDDAGTS GGPSSPPSDP PAMSPGPLDA LSSPTSVQEA DETTRSDISE RPSVDDIESE TGSTGALETR SLKDHKVSFL RSGTKLIFRR RPRQKEAGLS QSHDDLSNAT ATPSVRKKAG SFSRRLIKRF SFKSKPKANG NPSPQL
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