Cytochrome c oxidase subunit 7A2-like…

About Cytochrome c oxidase subunit 7A2-like, mitochondrial

Cytochrome c oxidase subunit 7A2-like, mitochondrial (COX7A2L) is a protein from Homo sapiens identified by UniProt accession O14548, 114 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 7A2-like, mitochondrial
UniProt accession	O14548
Gene	COX7A2L
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (65)

Diseases linked to this target (Open Targets).

lean body mass · score 0.33
body height · score 0.33
appendicular lean mass · score 0.32
fat body mass · score 0.27
forced expiratory volume · score 0.25
sitting height measurement · score 0.23
whole body water mass · score 0.22
base metabolic rate measurement · score 0.22
IGF-1 measurement · score 0.19
squamous cell lung carcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14548-F1	alphafold	PREDICTED	79.60	—

Amino-acid sequence (114 residues)

MYYKFSGFTQ KLAGAWASEA YSPQGLKPVV STEAPPIIFA TPTKLTSDST VYDYAGKNKV PELQKFFQKA DGVPVYLKRG LPDQMLYRTT MALTVGGTIY CLIALYMASQ PKNK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Cytochrome c oxidase subunit 7A2-like, mitochondrial (COX7A2L)