About Heat shock protein beta-6
Heat shock protein beta-6 (HSPB6) is a protein
from Homo sapiens identified by UniProt accession
O14558, 160 residues long.
MolForge cross-references it against 0 known binders and
167 disease associations.
Target properties
| Protein name | Heat shock protein beta-6 |
|---|
| UniProt accession | O14558 |
|---|
| Gene | HSPB6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 160 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (167)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.13
- hepatocellular carcinoma · score 0.10
- mathematical ability · score 0.10
- white matter microstructure measurement · score 0.09
- age at first sexual intercourse measurement · score 0.09
- body height · score 0.08
- calf circumference measurement · score 0.08
- breast cancer · score 0.08
- blood protein measurement · score 0.07
- age at menarche · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14558-F1 | alphafold | PREDICTED | 74.16 | — |
Amino-acid sequence (160 residues)
MEIPVPVQPS WLRRASAPLP GLSAPGRLFD QRFGEGLLEA ELAALCPTTL APYYLRAPSV ALPVAQVPTD PGHFSVLLDV KHFSPEEIAV KVVGEHVEVH ARHEERPDEH GFVAREFHRR YRLPPGVDPA AVTSALSPEG VLSIQAAPAS AQAPPPAAAK
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