Acyl carrier protein, mitochondrial (NDUFAB1)

About Acyl carrier protein, mitochondrial

Acyl carrier protein, mitochondrial (NDUFAB1) is a protein from Homo sapiens identified by UniProt accession O14561, 156 residues long. MolForge cross-references it against 0 known binders and 426 disease associations.

Target properties

Protein name	Acyl carrier protein, mitochondrial
UniProt accession	O14561
Gene	NDUFAB1
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (426)

Diseases linked to this target (Open Targets).

type 2 diabetes mellitus · score 0.61
diabetes mellitus · score 0.60
polycystic ovary syndrome · score 0.60
type 1 diabetes mellitus · score 0.58
gestational diabetes · score 0.58
obesity · score 0.57
prediabetes syndrome · score 0.56
neurodegenerative disease · score 0.56
insulin resistance · score 0.55
schizophrenia · score 0.55

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14561-F1	alphafold	PREDICTED	77.74	—

Amino-acid sequence (156 residues)

MASRVLSAYV SRLPAAFAPL PRVRMLAVAR PLSTALCSAG TQTRLGTLQP ALVLAQVPGR VTQLCRQYSD MPPLTLEGIQ DRVLYVLKLY DKIDPEKLSV NSHFMKDLGL DSLDQVEIIM AMEDEFGFEI PDIDAEKLMC PQEIVDYIAD KKDVYE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards