Ubiquitin domain-containing protein UBFD1 (UBFD1)

About Ubiquitin domain-containing protein UBFD1

Ubiquitin domain-containing protein UBFD1 (UBFD1) is a protein from Homo sapiens identified by UniProt accession O14562, 309 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Ubiquitin domain-containing protein UBFD1
UniProt accession	O14562
Gene	UBFD1
Organism	Homo sapiens
Length	309 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.28
mean corpuscular volume · score 0.06
cancer · score 0.00
Alzheimer disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14562-F1	alphafold	PREDICTED	70.26	—

Amino-acid sequence (309 residues)

MAAAGAPDGM EEPGMDTEAE TVATEAPARP VNCLEAEAAA GAAAEDSGAA RGSLQPAPAQ PPGDPAAQAS VSNGEDAGGG AGRELVDLKI IWNKTKHDVK FPLDSTGSEL KQKIHSITGL PPAMQKVMYK GLVPEDKTLR EIKVTSGAKI MVVGSTINDV LAVNTPKDAA QQDAKAEENK KEPLCRQKQH RKVLDKGKPE DVMPSVKGAQ ERLPTVPLSG MYNKSGGKVR LTFKLEQDQL WIGTKERTEK LPMGSIKNVV SEPIEGHEDY HMMAFQLGPT EASYYWVYWV PTQYVDAIKD TVLGKWQYF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards