DNA-binding protein RFXANK (RFXANK)

About DNA-binding protein RFXANK

DNA-binding protein RFXANK (RFXANK) is a protein from Homo sapiens identified by UniProt accession O14593, 260 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	DNA-binding protein RFXANK
UniProt accession	O14593
Gene	RFXANK
Organism	Homo sapiens
Length	260 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14593-F1	alphafold	PREDICTED	78.07	—

Amino-acid sequence (260 residues)

MELTQPAEDL IQTQQTPASE LGDPEDPGEE AADGSDTVVL SLFPCTPEPV NPEPDASVSS PQAGSSLKHS TTLTNRQRGN EVSALPATLD SLSIHQLAAQ GELDQLKEHL RKGDNLVNKP DERGFTPLIW ASAFGEIETV RFLLEWGADP HILAKERESA LSLASTGGYT DIVGLLLERD VDINIYDWNG GTPLLYAVRG NHVKCVEALL ARGADLTTEA DSGYTPMDLA VALGYRKVQQ VIENHILKLF QSNLVPADPE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards