Testis-specific basic protein Y 1 (VCY)

About Testis-specific basic protein Y 1

Testis-specific basic protein Y 1 (VCY) is a protein from Homo sapiens identified by UniProt accession O14598, 125 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Testis-specific basic protein Y 1
UniProt accession	O14598
Gene	VCY
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

azoospermia · score 0.01
Azoospermia · score 0.01
small cell osteogenic sarcoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14598-F1	alphafold	PREDICTED	64.12	—

Amino-acid sequence (125 residues)

MSPKPRASGP PAKAKETGKR KSSSQPSPSG PKKKTTKVAE KGEAVRGGRR GKKGAATKMA AVTAPEAESG PAAPGPSDQP SQELPQHELP PEEPVSEGTQ HDPLSQESEL EEPLSKGRPS TPLSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards