Testis-specific basic protein Y 2 (BPY2)

About Testis-specific basic protein Y 2

Testis-specific basic protein Y 2 (BPY2) is a protein from Homo sapiens identified by UniProt accession O14599, 106 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Testis-specific basic protein Y 2
UniProt accession	O14599
Gene	BPY2
Organism	Homo sapiens
Length	106 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

Infertility · score 0.02
male infertility · score 0.01
azoospermia · score 0.01
hepatocellular carcinoma · score 0.01
small cell osteogenic sarcoma · score 0.00
Azoospermia · score 0.00
cancer · score 0.00
neoplasm · score 0.00
gonadoblastoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14599-F1	alphafold	PREDICTED	41.53	—

Amino-acid sequence (106 residues)

MMTLVPRART RAGQDHYSHP CPRFSQVLLT EGIMTYCLTK NLSDVNILHR LLKNGNVRNT LLQSKVGLLT YYVKLYPGEV TLLTRPSIQM RLCCITGSVS RPRSQK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards