PTPN13-like protein, Y-linked (PRY)

About PTPN13-like protein, Y-linked

PTPN13-like protein, Y-linked (PRY) is a protein from Homo sapiens identified by UniProt accession O14603, 147 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	PTPN13-like protein, Y-linked
UniProt accession	O14603
Gene	PRY
Organism	Homo sapiens
Length	147 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

azoospermia · score 0.01
Azoospermia · score 0.01
male infertility · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14603-F1	alphafold	PREDICTED	42.62	—

Amino-acid sequence (147 residues)

MGATGLGFLL SWRQDNLNGT DCQGCNILYF SETTGSMCSE LSLNRGLEAR RKKDLKDSFL WRYGKVGCIS LPLREMTAWI NPPQISEIFQ GYHQRVHGAD ALSLQTNSLR SRLSSQCLGQ SFLLRTLERG RGFRALGDIC GHVHEED

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards