About Cdc42 effector protein 2
Cdc42 effector protein 2 (CDC42EP2) is a protein
from Homo sapiens identified by UniProt accession
O14613, 210 residues long.
MolForge cross-references it against 0 known binders and
36 disease associations.
Target properties
| Protein name | Cdc42 effector protein 2 |
|---|
| UniProt accession | O14613 |
|---|
| Gene | CDC42EP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 210 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (36)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.18
- mean corpuscular volume · score 0.15
- mean corpuscular hemoglobin · score 0.10
- red blood cell density measurement · score 0.06
- body height · score 0.03
- mean corpuscular hemoglobin concentration · score 0.03
- cancer · score 0.02
- lean body mass · score 0.02
- sex hormone-binding globulin measurement · score 0.02
- serum alanine aminotransferase measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O14613-F1 | alphafold | PREDICTED | 61.65 | — |
Amino-acid sequence (210 residues)
MSTKVPIYLK RGSRKGKKEK LRDLLSSDMI SPPLGDFRHT IHIGSGGGSD MFGDISFLQG KFHLLPGTMV EGPEEDGTFD LPFQFTRTAT VCGRELPDGP SPLLKNAISL PVIGGPQALT LPTAQAPPKP PRLHLETPQP SPQEGGSVDI WRIPETGSPN SGLTPESGAE EPFLSNASSL LSLHVDLGPS ILDDVLQIMD QDLDSMQIPT
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