C-X-C motif chemokine 11 (CXCL11)

About C-X-C motif chemokine 11

C-X-C motif chemokine 11 (CXCL11) is a protein from Homo sapiens identified by UniProt accession O14625, 94 residues long. MolForge cross-references it against 0 known binders and 461 disease associations.

Target properties

Protein name	C-X-C motif chemokine 11
UniProt accession	O14625
Gene	CXCL11
Organism	Homo sapiens
Length	94 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (461)

Diseases linked to this target (Open Targets).

C-X-C motif chemokine 11 measurement · score 0.21
blood protein measurement · score 0.19
protein measurement · score 0.17
fetal genotype effect measurement · score 0.16
inflammatory bowel disease · score 0.12
neoplasm · score 0.11
cancer · score 0.11
hepatocellular carcinoma · score 0.10
glioblastoma multiforme · score 0.08
breast cancer · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O14625-F1	alphafold	PREDICTED	79.96	—

Amino-acid sequence (94 residues)

MSVKGMAIAL AVILCATVVQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards